Mutation Information
Mutation Site
|
A71T |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
PR |
Genotype/Subtype
|
B |
Country
|
Brazilian |
Literature Information
PubMed PMID
|
18992847
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2009 |
Journal
|
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases |
Title
|
Distinct resistance mutation and polymorphism acquisition in HIV-1 protease of subtypes B and F1 from children and adult patients under virological failure. |
Author
|
Dumans AT,Barreto CC,Santos AF,Arruda M,Sousa TM,Machado ES,Sabino EC,Brindeiro RM,Tanuri A,Duarte AJ,Soares MA |
Evidence
|
In untreated patients, mutations L10V, K20R, and M36I were more frequent in subtype F1, while L63P, A71T, and V77I were more prevalent in subtype B. In treated patients, K20M, D30N, G73S, I84V, and L90M, were more prevalent in subtype B, and K20T and N88S were more prevalent in subtype F1.
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