HPV Mutation Detail Information

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Mutation Information

Mutation Site	A6964C
Mutation Type	Nucleotide level
Gene/Protein/Region Type	L1
Nucleotide_Mutation	K442N
Genotype/Subtype	HPV16
Viral Reference	U89348
Country	India

Literature Information

PubMed PMID	18199779
Disease	Cervical carcinoma
Published Year	2008
Journal	Journal of clinical microbiology
Title	Human papillomavirus type 16 variant analysis of E6, E7, and L1 genes and long control region in biopsy samples from cervical cancer patients in north India.
Author	Pande S,Jain N,Prusty BK,Bhambhani S,Gupta S,Sharma R,Batra S,Das BC
Evidence	Of four variants found independently (Fig. (Fig.2),2), two were silent mutations, A6667C and A6691G, coding for serine at codons 343 and 351, whereas A6803T and A6964C led to the missense mutations threonine→serine (T389S) and lysine→asparagine (K442N). The most frequently detected L1 variation, A6695C (Fig. (Fig.1c),1c), was found in six (54.5%) cases.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation