|
Mutation Information
|
Mutation Site
|
A6562G |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
L1 |
|
Genotype/Subtype
|
HPV59 |
|
Viral Reference
|
X77858
|
|
Country
|
Netherls |
Literature Information
|
PubMed PMID
|
32907991
|
|
Disease
|
HPV infection
|
|
Published Year
|
2020 |
|
Journal
|
Journal of clinical microbiology |
|
Title
|
Evidence for Missing Positive Results for Human Papilloma Virus 45 (HPV-45) and HPV-59 with the SPF10-DEIA-LiPA25 (Version 1) Platform Compared to Type-Specific Real-Time Quantitative PCR Assays and Impact on Vaccine Effectiveness Estimates. |
|
Author
|
van Eer K,Leussink S,Severs TT,van Marm-Wattimena N,Woestenberg PJ,Bogaards JA,King AJ |
|
Evidence
|
Sanger sequencing showed no phylogenetic distinction between SPF10-missed and SPF10-detected HPV-59 variants, but variants bearing the A6562G single-nucleotide polymorphism (SNP) in the SPF10 target region were more likely to be missed (P = 0.0392).
|
|
|
HPV Mutation Detail Information