Mutation Information
Mutation Site
|
A645C |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
E7 |
Nucleotide_Mutation
|
N29S |
Genotype/Subtype
|
HPV16 |
Viral Reference
|
K02718.1
|
Country
|
China |
Literature Information
PubMed PMID
|
21593270
|
Disease
|
Cervical carcinoma
|
Published Year
|
2011 |
Journal
|
Journal of clinical microbiology |
Title
|
Human papillomavirus type 16 variant analysis of E6, E7, and L1 [corrected] genes and long control region in [corrected] cervical carcinomas in patients in northeast China. |
Author
|
Shang Q,Wang Y,Fang Y,Wei L,Chen S,Sun Y,Li B,Zhang F,Gu H |
Evidence
|
Forty-four (84.62%) patients showed six mutation sites for the E7 gene, of which two, A645C and A647G, were missense mutations: asparagine→serine (N29S) and leucine→phenylalanine (L28F).
|
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