|
Mutation Information
|
Mutation Site
|
A60V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PreS |
|
Amino acid_Mutation
|
C3026A |
|
Genotype/Subtype
|
C |
|
Country
|
Japan |
Literature Information
|
PubMed PMID
|
17888035
|
|
Disease
|
Chronic hepatitis B;
Hepatocellular carcinoma
|
|
Published Year
|
2007 |
|
Journal
|
Cancer science |
|
Title
|
Analysis of the complete hepatitis B virus genome in patients with genotype C chronic hepatitis and hepatocellular carcinoma. |
|
Author
|
Zhang KY,Imazeki F,Fukai K,Arai M,Kanda T,Mikata R,Yokosuka O |
|
Evidence
|
At the end of follow‐up, a comparison of the mutation frequency in the HCC group and the non‐HCC group showed statistically significant substitution from adenine to guanine at 1317 (G1317A, hereafter) (14/23 vs 5/20, P = 0.03), T1341C/A/G (7/23 vs 0/20, P = 0.01), and C3026A/T (6/23 vs 0/20, P = 0.02) (Table 7).
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HBV Mutation Detail Information