Mutation Information
Mutation Site
|
A502F |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Literature Information
PubMed PMID
|
33715562
|
Published Year
|
2021 |
Journal
|
Journal of enzyme inhibition and medicinal chemistry |
Title
|
Flavonoids and Acid-Hydrolysis derivatives of Neo-Clerodane diterpenes from Teucrium flavum subsp. glaucum as inhibitors of the HIV-1 reverse transcriptase-associated RNase H function. |
Author
|
Fois B,Corona A,Tramontano E,Distinto S,Maccioni E,Meleddu R,Caboni P,Floris C,Cottiglia F |
Evidence
|
The next mutation involved the residue A502 located in the alpha helix, close to the second identified allosteric binding pocket.
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