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Mutation Information
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Mutation Site
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A4609G |
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Mutation Type
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Nucleotide level |
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Gene/Protein/Region Type
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L2 |
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Genotype/Subtype
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HPV58 |
Literature Information
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PubMed PMID
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28794033
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Published Year
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2017 |
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Journal
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Journal of virology |
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Title
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Ancient Evolution and Dispersion of Human Papillomavirus 58 Variants. |
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Author
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Chen Z,Ho WCS,Boon SS,Law PTY,Chan MCW,DeSalle R,Burk RD,Chan PKS |
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Evidence
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For example, the A3 sublineage-specific nucleotide variations of E7 C632T (amino acid T20I); E1 C1965T; E2 A3685G; NCR2 A4192C; L2 G4570A, A4609G, and A4935C (N231T); L2/L1 A5579C (L2 M446L or L1 L5F); L1 T5747C; and LCR G7147T, G7194C, A7304G, A7714C, and A7755G are highly correlated and represent fixed changes in natural selection when sublineage A3 split from its most recent common ancestor (MRCA).
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HPV Mutation Detail Information