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Mutation Information
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Mutation Site
|
A4041C |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
E5 |
|
Combined Mutation
|
e5.A4041G+e5.A4041C |
|
Nucleotide_Mutation
|
I65L |
|
Genotype/Subtype
|
HPV16 |
|
Country
|
Romania |
Literature Information
|
PubMed PMID
|
25143263
|
|
Disease
|
Cervical carcinoma;
Squamous-cell carcinoma;
Cervical intraepithelial neoplasia
|
|
Published Year
|
2014 |
|
Journal
|
Archives of virology |
|
Title
|
Molecular variants of human papilloma virus 16 E2, E4, E5, E6 and E7 genes associated with cervical neoplasia in Romanian patients. |
|
Author
|
Plesa A,Anton G,Iancu IV,Diaconu CC,Huica I,Stanescu AD,Socolov D,Nistor E,Popa E,Stoian M,Botezatu A |
|
Evidence
|
The most prevalent missense mutations in HPV16 E5 found in this study were as follows: T3904A, T3910C, G3919C, T3928C, A3978C, T3988C, T3991G, T4033C, A4041G/C, leading to amino acid changes (F19I; V21A; C24S; L27P; I44L; L47S; L48A; V62A; I65V/L).
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HPV Mutation Detail Information