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HIV Mutation Detail Information

> A364V Search Result


Mutation Information
Mutation Site A364V
Mutation Type Amino acid level
Gene/Protein/Region Type Gag
Relevant Drug PIs
Literature Information
PubMed PMID 27090171
Published Year 2016
Journal Antimicrobial agents and chemotherapy
Title Identification and Characterization of BMS-955176, a Second-Generation HIV-1 Maturation Inhibitor with Improved Potency, Antiviral Spectrum, and Gag Polymorphic Coverage.
Author Nowicka-Sans B,Protack T,Lin Z,Li Z,Zhang S,Sun Y,Samanta H,Terry B,Liu Z,Chen Y,Sin N,Sit SY,Swidorski JJ,Chen J,Venables BL,Healy M,Meanwell NA,Cockett M,Hanumegowda U,Regueiro-Ren A,Krystal M,Dicker IB
Evidence 293T cells were treated with BMS-955176 (200 nM or 0 nM) and then transfected (TransIT-LT1 transfection reagent MIR 2300; Mirus, Bio LLC) with pNLRepRlucP373S or pNLRepRlucP373S/A364V DNA.
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation