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HIV Mutation Detail Information

> A360T Search Result


Mutation Information
Mutation Site A360T
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Literature Information
PubMed PMID 18547911
Published Year 2008
Journal The Journal of biological chemistry
Title Connection domain mutations N348I and A360V in HIV-1 reverse transcriptase enhance resistance to 3'-azido-3'-deoxythymidine through both RNase H-dependent and -independent mechanisms.
Author Ehteshami M,Beilhartz GL,Scarth BJ,Tchesnokov EP,McCormick S,Wynhoven B,Harrigan PR,Götte M
Evidence The increase in prevalence at codon 360 was driven in part by a modest increase in the prevalence of a common polymorphism A360T, but predominantly by an increase in the A360V substitution.
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation