HIV Mutation Detail Information

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Mutation Information
Mutation Site A319T
Mutation Type Amino acid level
Gene/Protein/Region Type Env
Country America
Literature Information
PubMed PMID 29672607
Disease HIV infection/AIDS
Published Year 2018
Journal PLoS pathogens
Title Infant transmitted/founder HIV-1 viruses from peripartum transmission are neutralization resistant to paired maternal plasma.
Author Kumar A,Smith CEP,Giorgi EE,Eudailey J,Martinez DR,Yusim K,Douglas AO,Stamper L,McGuire E,LaBranche CC,Montefiori DC,Fouda GG,Gao F,Permar SR
Evidence We examined the highly variable N and C-terminal region amino acid residues K305Q, I307T, H308T, R315Q, F317L, A319T, and D322R (Fig 7), 3 of which (K305Q, I307T, and H308T) have previously been identified critical targets of the V3-specific IgG responses associated with reduced MTCT risk.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation