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Mutation Information
|
Mutation Site
|
A3120T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreS |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
20419326
|
|
Disease
|
HBV infection;
Liver cirrhosis;
Hepatocellular carcinoma
|
|
Published Year
|
2010 |
|
Journal
|
Journal of gastroenterology |
|
Title
|
Significant association of different preS mutations with hepatitis B-related cirrhosis or hepatocellular carcinoma. |
|
Author
|
Yin J,Xie J,Zhang H,Shen Q,Han L,Lu W,Han Y,Li C,Ni W,Wang H,Cao G |
|
Evidence
|
C2875A, G2946C, G2950A, G2951A, A2962G, C2964A, T3066A, T3069G, C3116T, A3120T, C7A, and T53C were inversely associated with the risk of LC compared with ASCs and the CHB patients, whereas these mutations were significantly associated with an increased risk of HCC compared with the HBV-infected subjects without HCC.
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HBV Mutation Detail Information