Mutation Information
Mutation Site
|
A30L |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Vpr |
Literature Information
PubMed PMID
|
27343732
|
Published Year
|
2016 |
Journal
|
Virology |
Title
|
HIV-1 Vpr increases Env expression by preventing Env from endoplasmic reticulum-associated protein degradation (ERAD). |
Author
|
Zhang X,Zhou T,Frabutt DA,Zheng YH |
Evidence
|
The Vpr activity depends on its N-terminal region, which was disrupted by a single A30L mutation.
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