|
Mutation Information
|
Mutation Site
|
A21T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Country
|
Cameroon |
Literature Information
|
PubMed PMID
|
32106437
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2020 |
|
Journal
|
International journal of molecular sciences |
|
Title
|
Variability in HIV-1 Integrase Gene and 3'-Polypurine Tract Sequences in Cameroon Clinical Isolates, and Implications for Integrase Inhibitors Efficacy. |
|
Author
|
Acharya A,Tagny CT,Mbanya D,Fonsah JY,Nchindap E,Kenmogne L,Jihyun M,Njamnshi AK,Kanmogne GD |
|
Evidence
|
For the cohort group, polymorphisms A21T, I72V, D167E, and D256E were significantly more prevalent in non-AG (24-48%) than in AG (5-20%) samples (p < 0.04, Table 5) and K136Q was only present in non-AG (44%) samples (p < 0.000001, Table 5).
|
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HIV Mutation Detail Information