HBV Mutation Detail Information

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Mutation Information

Mutation Site	A2189T
Mutation Type	Nucleotide level
Gene/Protein/Region Type	C
Genotype/Subtype	B
Country	China

Literature Information

PubMed PMID	25849554
Disease	Acute on chronic liver failure
Published Year	2015
Journal	PloS one
Title	New point mutations in surface and core genes of hepatitis B virus associated with acute on chronic liver failure identified by complete genomic sequencing.
Author	Xu H,Zhao M,Lou G,Zheng M,Cao Q,Chen Z
Evidence	As compared with non-ACLF cases, T216C, G285A, A1846T/G, G1896A, C1913A/G, A2159G/C, A2189T/C in genotype B and G285A, A1846T/G, G1896A, C1913A/G and A2159G/C in genotype C were significantly associated with an increased risk of ACLF

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation