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Mutation Information
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Mutation Site
|
A2159G |
|
Mutation Type
|
Nucleotide level |
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Gene/Protein/Region Type
|
C |
|
Viral Reference
|
GU434373.1;
GU434374.1 |
|
Country
|
China |
Literature Information
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PubMed PMID
|
20699378
|
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Disease
|
Hepatocellular carcinoma
|
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Published Year
|
2010 |
|
Journal
|
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology |
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Title
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Comparison study on the complete sequence of hepatitis B virus identifies new mutations in core gene associated with hepatocellular carcinoma. |
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Author
|
Zhu Y,Jin Y,Guo X,Bai X,Chen T,Wang J,Qian G,Groopman JD,Gu J,Li J,Tu H |
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Evidence
|
RESULTS: The pre-S deletion and 12 point mutations, namely, the pre-S2 start codon mutation, T53C in the pre-S2 gene, T766A in the S gene, G1613A, C1653T, A1762T, G1764A in the X gene, and G1899A, C2002T, A2159G, A2189C, and G2203W (A or T) in the pre-C/C gene, showed close associations with HCC.
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HBV Mutation Detail Information