|
Mutation Information
|
Mutation Site
|
A1899G |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreC |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
19946588
|
|
Disease
|
Acute hepatitis B;
HBV-HIV coinfection
|
|
Published Year
|
2009 |
|
Journal
|
Journal of medical case reports |
|
Title
|
Virological pattern of hepatitis B infection in an HIV-positive man with fatal fulminant hepatitis B: a case report. |
|
Author
|
Bagaglio S,Albarello L,Biswas P,Uberti-Foppa C,Fortis C,Morsica G |
|
Evidence
|
A homogeneous population of a pre-core mutant strain harbouring the A1896G and A1899G affecting HBeAg expression was invariably found in the liver tissue, plasma and peripheral blood mononuclear cells despite active HBeAg secretion
|
|
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HBV Mutation Detail Information