EBV Mutation Detail Information

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Mutation Information

Mutation Site	A185K
Mutation Type	Amino acid level
Gene/Protein/Region Type	BZLF1

Literature Information

PubMed PMID	9123876
Published Year	1997
Journal	Virology
Title	The bZip dimerization domain of the Epstein-Barr virus BZLF1 (Z) protein mediates lymphoid-specific negative regulation.
Author	Hong Y,Holley-Guthrie E,Kenney S
Evidence	The plasmid CMV-Z311 (derived from the SV40-driven Z311 vector, a gift from Alain Sergeant) (Giotet al.,1991) contains the Z cDNA, with a site-directed mutation (an alanine to lysine switch at amino acid 185) within thehumidified atmosphere containing 5% CO2 DNA-binding domain, cloned into the pHD1013 vector This mutation greatly reduces the DNA-binding functionPlasmids.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation