EBV Mutation Detail Information

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Mutation Information
Mutation Site A185K
Mutation Type Amino acid level
Gene/Protein/Region Type BZLF1
Literature Information
PubMed PMID 16940523
Published Year 2006
Journal Journal of virology
Title Amino acids in the basic domain of Epstein-Barr virus ZEBRA protein play distinct roles in DNA binding, activation of early lytic gene expression, and promotion of viral DNA replication.
Author Heston L,El-Guindy A,Countryman J,Dela Cruz C,Delecluse HJ,Miller G
Evidence The R183A, A185K, A185V, C189A, and R190A mutants were markedly impaired in DNA binding (<10% of that of the wild type).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation