|
Mutation Information
|
Mutation Site
|
A1846T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
PreC |
Literature Information
|
PubMed PMID
|
26063382
|
|
Disease
|
Acute on chronic liver failure;
Chronic hepatitis B
|
|
Published Year
|
2015 |
|
Journal
|
Virology journal |
|
Title
|
Associations between hepatitis B virus basal core promoter/pre-core region mutations and the risk of acute-on-chronic liver failure: a meta-analysis. |
|
Author
|
Hu F,Bi S,Yan H,Shi Y,Sheng J |
|
Evidence
|
Several mutations were significantly correlated with ACLF: T1753V (1.889, 95 % confidence interval (CI) [1.357-2.631]), A1762T (2.696 [2.265-3.207]), G1764A (3.005 [2.077-4.347]), A1762T/G1764A (2.379 [1.519-3.727]), C1766T (1.849 [1.403-2.437]), T1768A (2.440 [1.405-3.494]), A1846T (3.163 [2.157-4.639]), G1896A (2.181 [1.800-2.642]), G1899A (3.569 [2.906-4.385]) and G1896A/A1762T/G1764A (1.575 [1.172-2.116]).
|
|
|
HBV Mutation Detail Information