HBV Mutation Detail Information

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Mutation Information

Mutation Site	A1846T
Mutation Type	Nucleotide level
Gene/Protein/Region Type	PreC
Genotype/Subtype	B;C
Country	China

Literature Information

PubMed PMID	25822176
Disease	Chronic hepatitis B
Published Year	2015
Journal	PloS one
Title	Lower mutation frequency of BCP/precore regions in e antigen-negative chronic HBV-infected children instead of adults patients.
Author	Huang Y,Deng H,Shan X,Gong X,Li X,Tu Z,Long Q,Huang A
Evidence	Notably, the frequency of the G1896A mutation in the HBeAg-negative child patients was significantly lower than in the HBeAg-negative adult patients (41.1% vs 91.7%, P < 0.001), and similar results were also observed for other BCP/precore mutations such as A1846T (17.8% vs 37.5%, P = 0.010) and the G1899A substitution (7.8% vs 20.8%, P = 0.026).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation