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HBV Mutation Detail Information

> A1846T Search Result


Mutation Information
Mutation Site A1846T
Mutation Type Nucleotide level
Gene/Protein/Region Type PreC
Genotype/Subtype B
Country China
Literature Information
PubMed PMID 21739444
Disease Acute on chronic liver failure
Published Year 2011
Journal Journal of medical virology
Title Hepatitis B virus genotype B with G1896A and A1762T/G1764A mutations is associated with hepatitis B related acute-on-chronic liver failure.
Author Xiao L,Zhou B,Gao H,Ma S,Yang G,Xu M,Abbott WG,Chen J,Sun J,Wang Z,Hou J
Evidence In genotype B patients, the A1762T/G1764A, A1846T, and G1896A mutations were significantly more prevalent in patients with acute-on-chronic liver failure than CHB (50.7% vs. 28.0%, P = 0.004; 59.2% vs. 34.1%, P = 0.002; 69.0% vs. 41.5%, P = 0.001, respectively).
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation