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Mutation Information
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Mutation Site
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A1846T |
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Mutation Type
|
Nucleotide level |
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Gene/Protein/Region Type
|
PreC |
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Viral Reference
|
AY090460;
AY090457;
AY090454;
AF405706;
AB064310;
AF160501;
AF223965;
AB036910;
X69798;
AB032431;
X75657;
X85254;
M32138;
X65259;
AB014381;
M12906;
X04615;
AB033554;
AF100309;
D00329;
AF090842;
X51970;
X02763 |
|
Country
|
China |
Literature Information
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PubMed PMID
|
20848146
|
|
Disease
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Chronic hepatitis B;
Acute on chronic liver failure
|
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Published Year
|
2011 |
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Journal
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Journal of gastroenterology |
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Title
|
Association of hepatitis B virus mutations in basal core promoter and precore regions with severity of liver disease: an investigation of 793 Chinese patients with mild and severe chronic hepatitis B and acute-on-chronic liver failure. |
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Author
|
Xu Z,Ren X,Liu Y,Li X,Bai S,Zhong Y,Wang L,Mao P,Wang H,Xin S,Wong VW,Chan HL,Zoulim F,Xu D |
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Evidence
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N addition to the ten interested sites, significant difference in variant frequencies among the three illness categories was also found at A1846T (CHB-M 8.3%, CHB-S 36.5%, ACLF 37.5%, P < 0.01).
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HBV Mutation Detail Information