Mutation Information
Mutation Site
|
A1814T |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
PreC |
Viral Reference
|
X02763;
AF297622 |
Country
|
South Africa |
Literature Information
PubMed PMID
|
23925707
|
Disease
|
HBV-HIV coinfection
|
Published Year
|
2013 |
Journal
|
Journal of medical virology |
Title
|
Variability of the preC/C region of hepatitis B virus genotype A from a South African cohort predominantly infected with HIV. |
Author
|
Mayaphi SH,Martin DJ,Mphahlele MJ,Blackard JT,Bowyer SM |
Evidence
|
The finding that 24% (6) of the study participants had preC start codon mutations (A1814C/T and G1816T) suggests that mutations that lead to failure of HBeAg production are common in subgenotype A1.
|
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