HBV Mutation Detail Information

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Mutation Information
Mutation Site A1814T
Mutation Type Nucleotide level
Gene/Protein/Region Type PreC
Country Sudan
Literature Information
PubMed PMID 23865777
Disease HBV associated liver disease
Published Year 2013
Journal BMC infectious diseases
Title Molecular characterization of hepatitis B virus in liver disease patients and asymptomatic carriers of the virus in Sudan.
Author Yousif M,Mudawi H,Bakhiet S,Glebe D,Kramvis A
Evidence In 22/49 HBeAg-negative sera, the absence of HBeAg was as a result of missense mutations affecting the translation of the HBeAg precursor: 18 had the classical stop codon mutation G1896A (p< 0.05, when comparing isolates from HBeAg-negative and -positive sera) and 4 had initiation codon mutations, 2 A1814T and 2 T1815C.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation