Mutation Information
Mutation Site
|
A1814T |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
PreC |
Country
|
Sudan |
Literature Information
PubMed PMID
|
23865777
|
Disease
|
HBV associated liver disease
|
Published Year
|
2013 |
Journal
|
BMC infectious diseases |
Title
|
Molecular characterization of hepatitis B virus in liver disease patients and asymptomatic carriers of the virus in Sudan. |
Author
|
Yousif M,Mudawi H,Bakhiet S,Glebe D,Kramvis A |
Evidence
|
In 22/49 HBeAg-negative sera, the absence of HBeAg was as a result of missense mutations affecting the translation of the HBeAg precursor: 18 had the classical stop codon mutation G1896A (p< 0.05, when comparing isolates from HBeAg-negative and -positive sera) and 4 had initiation codon mutations, 2 A1814T and 2 T1815C.
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