HIV Mutation Detail Information

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Mutation Information

Mutation Site	A179P
Mutation Type	Amino acid level
Gene/Protein/Region Type	IN

Literature Information

PubMed PMID	19014595
Published Year	2008
Journal	Retrovirology
Title	Contribution of the C-terminal region within the catalytic core domain of HIV-1 integrase to yeast lethality, chromatin binding and viral replication.
Author	Xu Z,Zheng Y,Ao Z,Clement M,Mouland AJ,Kalpana GV,Belhumeur P,Cohen EA,Yao X
Evidence	Our study identified three HIV-1 IN mutants, V165A, A179P and KR186,7AA, located in the C-terminal region of the catalytic core domain of IN that do not induce the lethal phenotype in yeast.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation