HBV Mutation Detail Information

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Mutation Information

Mutation Site	A1762T
Mutation Type	Nucleotide level
Gene/Protein/Region Type	BCP
Combined Mutation	bcp.G1764A+bcp.A1762T
Country	Germany

Literature Information

PubMed PMID	33055418
Disease	HBV infection
Published Year	2020
Journal	JCI insight
Title	Quadruple mutation GCAC1809-1812TTCT acts as a biomarker in healthy European HBV carriers.
Author	Peiffer KH,Spengler C,Basic M,Jiang B,Kuhnhenn L,Obermann W,Zahn T,Glitscher M,Loglio A,Facchetti F,Carra G,Kubesch A,Vermehren J,Knop V,Graf C,Dietz J,Finkelmeier F,Herrmann E,Trebicka J,Grünweller A,Zeuzem S,Sarrazin C,Lampertico P,Hildt E
Evidence	GCAC1809-1812TTCT was strongly associated with coexistence of basal core promoter (BCP) double mutation A1762T/G1764A and lower HBV DNA levels.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation