Mutation Information
Mutation Site
|
A1762T |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
BCP |
Country
|
Argentina |
Literature Information
PubMed PMID
|
25822666
|
Disease
|
Acute exacerbation of chronic hepatitis B
|
Published Year
|
2015 |
Journal
|
PloS one |
Title
|
Hepatitis B virus genotype distribution and genotype-specific BCP/preCore substitutions in acute and chronic infections in Argentina. |
Author
|
González López Ledesma MM,Mojsiejczuk LN,Rodrigo B,Sevic I,Mammana L,Galdame O,Gadano A,Fainboim H,Campos R,Flichman D |
Evidence
|
In anti-HBe positive chronic infections, sgF1b was more prone to have A1762T/G1764A mutation than sgA2, sgF4 and gD (75.0, 40.0, 33.3 and 31.8%, p<0.005), whereas in the pC region, gD and sgF4 were more likely to have G1896A than sgA2 and sgF1b (81.0, 72.7, 0.0 and 31.3%, p <0.001).
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