HBV Mutation Detail Information

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Mutation Information

Mutation Site	A1762T
Mutation Type	Nucleotide level
Gene/Protein/Region Type	BCP
Genotype/Subtype	B;C
Country	China

Literature Information

PubMed PMID	25822176
Disease	Chronic hepatitis B
Published Year	2015
Journal	PloS one
Title	Lower mutation frequency of BCP/precore regions in e antigen-negative chronic HBV-infected children instead of adults patients.
Author	Huang Y,Deng H,Shan X,Gong X,Li X,Tu Z,Long Q,Huang A
Evidence	HBeAg seroconversion can be defined as a balance point in the battle between HBV and the host immune response. G1896A and the A1762T and G1764A double mutation are the most frequent isolated mutations in the precore and basal core promoter (BCP) regions of the HBV genome isolated from HBeAg-negative patients.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation