|
Mutation Information
|
Mutation Site
|
A1762T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Combined Mutation
|
bcp.G1764A+bcp.A1762T |
|
Genotype/Subtype
|
E |
|
Country
|
Sudan |
Literature Information
|
PubMed PMID
|
25449246
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2014 |
|
Journal
|
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases |
|
Title
|
Genotyping and virological characteristics of hepatitis B virus in HIV-infected individuals in Sudan. |
|
Author
|
Yousif M,Mudawi H,Hussein W,Mukhtar M,Nemeri O,Glebe D,Kramvis A |
|
Evidence
|
Of the six isolates from HBeAg-positive sera, two had mutations at the BCP: SDH052 (HBsAg-positive, genotype D) had A1762G, and SDH084 (HBsAg-positive, genotype E) had A1762T/G1764A. The remaining four isolates, from HBeAg-positive patients, had wild-type BCP/PC. Thirty of the 44 isolates from HBeAg-negative individuals (17 HBsAg-positive and 13 HBsAg-negative) were successfully amplified and sequenced in the BCP/PC region.
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HBV Mutation Detail Information