|
Mutation Information
|
Mutation Site
|
A1762T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Genotype/Subtype
|
B;C |
|
Country
|
Taiwan; China |
Literature Information
|
PubMed PMID
|
24763132
|
|
Disease
|
Liver cirrhosis
|
|
Published Year
|
2015 |
|
Journal
|
Gut |
|
Title
|
Higher proportion of viral basal core promoter mutant increases the risk of liver cirrhosis in hepatitis B carriers. |
|
Author
|
Tseng TC,Liu CJ,Yang HC,Chen CL,Yang WT,Tsai CS,Kuo SF,Verbree FC,Su TH,Wang CC,Liu CH,Chen PJ,Chen DS,Kao JH |
|
Evidence
|
BACKGROUND AND OBJECTIVE: Precore (PC) variant (G1896A) and basal core promoter (BCP) variant (A1762T/G1764A) of HBV are associated with risk of hepatocellular carcinoma in HBV carriers.
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|
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HBV Mutation Detail Information