HBV Mutation Detail Information

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Mutation Information

Mutation Site	A1762T
Mutation Type	Nucleotide level
Gene/Protein/Region Type	BCP
Genotype/Subtype	B;C
Country	China

Literature Information

PubMed PMID	24006435
Disease	Chronic hepatitis B
Published Year	2013
Journal	Journal of virology
Title	HLA-DP polymorphisms affect the outcomes of chronic hepatitis B virus infections, possibly through interacting with viral mutations.
Author	Zhang Q,Yin J,Zhang Y,Deng Y,Ji X,Du Y,Pu R,Han Y,Zhao J,Han X,Zhang H,Cao G
Evidence	Table 3 lists the HBV mutations in the EnhII/BCP/PC region that are significantly associated with HC and HCC. Of these, the C1653T, T1753C, A1762T/G1764A, and G1899A mutations in HBV genotype C and the A1762T/G1764A mutations in HBV genotype B increased in prevalence from the ASC state to HCC successively (Ptrend < 0.001 for each).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation