|
Mutation Information
|
Mutation Site
|
A1762T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Genotype/Subtype
|
C |
|
Viral Reference
|
NM_002918.3
|
|
Country
|
Hong Kong;China |
Literature Information
|
PubMed PMID
|
21814558
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2011 |
|
Journal
|
PloS one |
|
Title
|
The G1613A mutation in the HBV genome affects HBeAg expression and viral replication through altered core promoter activity. |
|
Author
|
Li MS,Lau TC,Chan SK,Wong CH,Ng PK,Sung JJ,Chan HL,Tsui SK |
|
Evidence
|
In BCP region, a double mutation, A1762T/G1764A, is commonly found to associate with HBV genotype C, which affects the viral replications.
|
|
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HBV Mutation Detail Information