|
Mutation Information
|
Mutation Site
|
A1762T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Combined Mutation
|
bcp.G1764A+bcp.A1762T |
|
Genotype/Subtype
|
C2 |
|
Viral Reference
|
GQ475316.1
|
|
Country
|
Finland |
Literature Information
|
PubMed PMID
|
21490166
|
|
Disease
|
Hepatocellular carcinoma;
Chronic hepatitis B
|
|
Published Year
|
2011 |
|
Journal
|
Clinical and vaccine immunology : CVI |
|
Title
|
Impact of hepatitis B virus (HBV) x gene mutations on hepatocellular carcinoma development in chronic HBV infection. |
|
Author
|
Lee JH,Han KH,Lee JM,Park JH,Kim HS |
|
Evidence
|
The hepatitis B virus (HBV) PreS mutations C1653T, T1753V, and A1762T/G1764A were reported as a strong risk factor of hepatocellular carcinoma (HCC) in a meta-analysis.
|
|
|
HBV Mutation Detail Information