HBV Mutation Detail Information

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Mutation Information

Mutation Site	A1762T
Mutation Type	Nucleotide level
Gene/Protein/Region Type	BCP
Combined Mutation	bcp.G1764A+bcp.A1762T
Genotype/Subtype	A

Literature Information

PubMed PMID	19263474
Published Year	2009
Journal	Hepatology (Baltimore, Md.)
Title	The rtA194T polymerase mutation impacts viral replication and susceptibility to tenofovir in hepatitis B e antigen-positive and hepatitis B e antigen-negative hepatitis B virus strains.
Author	Amini-Bavil-Olyaee S,Herbers U,Sheldon J,Luedde T,Trautwein C,Tacke F
Evidence	To introduce the PC mutant (G1896A/C1858T) and the BCP double mutations (A1762T/G1764A) to the rtA194T vectors, the EcoRI‐NcoI fragment was cut out from each of the rtA194T vectors and ligated into the same region within the WT‐PC and WT‐BCP 1.28‐fold HBV replication‐competent plasmids, respectively

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation