Mutation Information
Mutation Site
|
A1762T |
Mutation Type
|
Nucleotide level |
Gene/Protein/Region Type
|
C Promoter |
Literature Information
PubMed PMID
|
19008175
|
Disease
|
Liver cirrhosis
|
Published Year
|
2008 |
Journal
|
European journal of medical research |
Title
|
Core promoter mutant HBV non-responding to adefovir after viral breakthrough on lamivudine: rapid virologic response to tenofovir plus lamivudine in a cirrhotic patient. |
Author
|
Katsounas A,Jochum C,Canbay A,Schlaak J,Gerlich WH,Gerken G |
Evidence
|
Because of unchanged VL sequence analysis was performed three months later, which showed the mutation (rtS219A) and the concomitant mutation (sS210R) and 2 mutations in core promoter region (A1762T), (G1764A).
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