|
Mutation Information
|
Mutation Site
|
A1762T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
C Promoter |
|
Combined Mutation
|
c promoter.T1753C+c promoter.G1764A+c promoter.A1762T;c promoter.G1764A+c promoter.A1762T;prec.G1896A+c promoter.G1764A+c promoter.A1762T;c promoter.C1766T+c promoter.G1764A+c promoter.A1762T;c promoter.C1766T+c promoter.G1764A+c promoter.A1762T+c promoter.T1753C |
|
Genotype/Subtype
|
B;C |
|
Country
|
Vietnam |
Literature Information
|
PubMed PMID
|
17203204
|
|
Disease
|
Hepatocellular carcinoma;
Liver cirrhosis;
Chronic hepatitis B
|
|
Published Year
|
2007 |
|
Journal
|
International journal of molecular medicine |
|
Title
|
Genotype and variations in core promoter and pre-core regions are related to progression of disease in HBV-infected patients from Northern Vietnam. |
|
Author
|
Truong BX,Seo Y,Yano Y,Ho PT,Phuong TM,Long DV,Son NT,Long NC,Kato H,Hayashi Y,Trach NK,Kasuga M |
|
Evidence
|
The presence of the mutation A1762T/G1764A correlated with disease progression. The triple mutation T1753C/A1762T/ G1764A was quite common and was more prevalent in LC and HCC than in CH and ASC.
|
|
|
HBV Mutation Detail Information