HBV Mutation Detail Information

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Mutation Information

Mutation Site	A1762T
Mutation Type	Nucleotide level
Gene/Protein/Region Type	BCP
Combined Mutation	bcp.G1764A+bcp.A1762T

Literature Information

PubMed PMID	16928212
Disease	Chronic hepatitis B
Published Year	2006
Journal	Journal of gastroenterology and hepatology
Title	Association of core promoter mutations with viral breakthrough in chronic hepatitis B patients on long-term lamivudine therapy.
Author	Kazim SN,Chauhan R,Das BC,Sarin SK
Evidence	Core promoter mutations were seen in five of eight (62.5%) and in six of nine (66.6%); classic double mutations (A1762T/G1764A) of core promoter region were detected in two and three patients and novel double mutations of core promoter (G1764T/C1766G) in one patient each of group Ia and Ib patients, respectively.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation