|
Mutation Information
|
Mutation Site
|
A1762T |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
C Promoter |
|
Genotype/Subtype
|
A;D;F |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Korea |
Literature Information
|
PubMed PMID
|
15932365
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2005 |
|
Journal
|
Alimentary pharmacology & therapeutics |
|
Title
|
Changes in different regions of hepatitis B virus gene in hepatitis B 'e' antigen-negative patients with chronic hepatitis B: the effect of long-term lamivudine therapy. |
|
Author
|
Buti M,Jardi R,Rodriguez-Frias F,Valdes A,Schaper M,Esteban R,Guardia J |
|
Evidence
|
DNA sequence analysis of the core promoter region (nucleotides 1762 and 1764) showed that six patients had core promoter changes in the serum samples collected at baseline, both at nucleotide 1762 (A1762T) and at nucleotide 1764 (G1764A; Table 3).
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HBV Mutation Detail Information