HBV Mutation Detail Information

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Mutation Information

Mutation Site	A1752T
Mutation Type	Nucleotide level
Gene/Protein/Region Type	BCP
Genotype/Subtype	B;C
Country	China

Literature Information

PubMed PMID	26647737
Disease	Chronic hepatitis B
Published Year	2015
Journal	Scientific reports
Title	Deep sequencing of hepatitis B virus basal core promoter and precore mutants in HBeAg-positive chronic hepatitis B patients.
Author	Yan L,Zhang H,Ma H,Liu D,Li W,Kang Y,Yang R,Wang J,He G,Xie X,Wang H,Wei L,Lu Z,Shao Q,Chen H
Evidence	Amino acid transitions induced by G1719T, A1726C, A1752G/T and BCP A1762T/G1764A mutants had higher prevalence of 39.7% (23/58), 29.3% (17/58), 27.6% (16/58) and 31.0% (18/58), which mainly occurred in genotype C (21/23), genotype B (16/17), genotype B (13/16) and genotype C (16/18) infection patients, respectively.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation