HBV Mutation Detail Information

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Mutation Information
Mutation Site A1727G
Mutation Type Nucleotide level
Gene/Protein/Region Type EnhII
Country China
Literature Information
PubMed PMID 20959817
Disease Chronic hepatitis B; Liver cirrhosis; Hepatocellular carcinoma
Published Year 2011
Journal The American journal of gastroenterology
Title Association between the various mutations in viral core promoter region to different stages of hepatitis B, ranging of asymptomatic carrier state to hepatocellular carcinoma.
Author Yin J,Xie J,Liu S,Zhang H,Han L,Lu W,Shen Q,Xu G,Dong H,Shen J,Zhang J,Han J,Wang L,Liu Y,Wang F,Zhao J,Zhang Q,Ni W,Wang H,Cao G
Evidence As compared with ASCs and the patients with CHB,C1673T, T1674C, A1703G, A1726C, C1730G, C1799G, A1846T,and C1913A in genotype C and C1653T, G1719T, A1727G,T1753A / C, A1762T, G1764A, C1766T, T1768A, C1773T, and G1896A in both genotypes were signifi cantly associated with LC(see Supplementary Table 6 )

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation