|
Mutation Information
|
Mutation Site
|
A1678C |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
BCP |
|
Combined Mutation
|
c promoter.A1703T+bcp.A1678C |
|
Genotype/Subtype
|
D |
|
Viral Reference
|
J02203
|
|
Country
|
Tunisia |
Literature Information
|
PubMed PMID
|
22997074
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2012 |
|
Journal
|
Journal of medical virology |
|
Title
|
Frequency and clinical significance of core promoter and precore region mutations in Tunisian patients infected chronically with hepatitis B. |
|
Author
|
Ouneissa R,Bahri O,Alaya-Bouafif NB,Chouaieb S,Ben Yahia A,Sadraoui A,Hammami W,Filali N,Azzouz MM,Mami NB,Triki H |
|
Evidence
|
For local strains, this region of the genome is characterized by A1652G in replacement to C1653T and also a high frequency of two specific double mutations A1652G‐A1679G or A1678C‐A1703T.
|
|
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HBV Mutation Detail Information