Mutation Information
Mutation Site
|
A163X |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Gag |
Country
|
Durban; South Africa |
Literature Information
PubMed PMID
|
18369479
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2008 |
Journal
|
PLoS pathogens |
Title
|
Transmission of HIV-1 CTL escape variants provides HLA-mismatched recipients with a survival advantage. |
Author
|
Chopera DR,Woodman Z,Mlisana K,Mlotshwa M,Martin DP,Seoighe C,Treurnicht F,de Rosa DA,Hide W,Karim SA,Gray CM,Williamson C,CAPRISA 002 Study Team. |
Evidence
|
Apart from the potential immune evasion mutations at Gag positions 242 and 146, three sequences (CAP088, CAP228 and CAP255) also carried the well-studied A163X mutation in the HLA B*57/B*5801 restricted KF11 epitope (Figure 2).
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