HIV Mutation Detail Information

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Mutation Information
Mutation Site A163X
Mutation Type Amino acid level
Gene/Protein/Region Type Gag
Country Durban; South Africa
Literature Information
PubMed PMID 18369479
Disease HIV infection/AIDS
Published Year 2008
Journal PLoS pathogens
Title Transmission of HIV-1 CTL escape variants provides HLA-mismatched recipients with a survival advantage.
Author Chopera DR,Woodman Z,Mlisana K,Mlotshwa M,Martin DP,Seoighe C,Treurnicht F,de Rosa DA,Hide W,Karim SA,Gray CM,Williamson C,CAPRISA 002 Study Team.
Evidence Apart from the potential immune evasion mutations at Gag positions 242 and 146, three sequences (CAP088, CAP228 and CAP255) also carried the well-studied A163X mutation in the HLA B*57/B*5801 restricted KF11 epitope (Figure 2).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation