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Mutation Information
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Mutation Site
|
A163S |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Gag |
|
Country
|
Durban; South Africa |
Literature Information
|
PubMed PMID
|
18369479
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2008 |
|
Journal
|
PLoS pathogens |
|
Title
|
Transmission of HIV-1 CTL escape variants provides HLA-mismatched recipients with a survival advantage. |
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Author
|
Chopera DR,Woodman Z,Mlisana K,Mlotshwa M,Martin DP,Seoighe C,Treurnicht F,de Rosa DA,Hide W,Karim SA,Gray CM,Williamson C,CAPRISA 002 Study Team. |
|
Evidence
|
The optimal epitope within this peptide restricted by the host HLA (HLA-A*2601) is EVIPMFSAL and the observed KF11 A163S escape mutation falls outside this epitope.
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HIV Mutation Detail Information