Mutation Information
Mutation Site
|
A15S |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Nef |
Viral Reference
|
U46016
|
Country
|
Ethiopia |
Literature Information
PubMed PMID
|
31262272
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2019 |
Journal
|
BMC infectious diseases |
Title
|
A viral genome wide association study and genotypic resistance testing in patients failing first line antiretroviral therapy in the first large countrywide Ethiopian HIV cohort. |
Author
|
Telele NF,Kalu AW,Gebre-Selassie S,Fekade D,Marrone G,Grossmann S,Neogi U,Tegbaru B,Sönnerborg A |
Evidence
|
Mutations were also identified in the vif (N36K/S n = 4; G101S/D n = 4, V31I n = 3, K33R, R34K, K63R, R92G, G101D n = 2) and in the nef gene (A15E/S n = 3, L20I/A/R n = 3; W5R/Q, K7N, C8S, V11P/G, R19A/P, D24A/G, K105 N/T, K118E/R n = 2). The tat, vpu and vpr showed very few amino acid changes (Fig. (Fig.33).
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