Mutation Information
Mutation Site
|
A146T |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
Gag |
Viral Reference
|
NC001802
|
Immune Escape
|
Y |
Country
|
Brazil |
Literature Information
PubMed PMID
|
32711474
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2020 |
Journal
|
BMC infectious diseases |
Title
|
Immune escape mutations in HIV-1 controllers in the Brazilian Amazon region. |
Author
|
Gomes STM,da Silva Graça Amoras E,Gomes ÉR,Queiroz MAF,Júnior ECS,de Vasconcelos Massafra JM,da Silva Lemos P,Júnior JLV,Ishak R,Vallinoto ACR |
Evidence
|
In addition, two new mutations were identified, namely, a substitution from alanine to threonine at position 146 of the p24 protein (A146T;Fig. 2) in two individuals from the VC group and a phenylalanine substitution to leucine at position 383 of the p7 protein (F383L) in the NVC group.
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