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Mutation Information
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Mutation Site
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A136T |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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L1 |
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Genotype/Subtype
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HPV16 |
Literature Information
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PubMed PMID
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28968823
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Published Year
|
2017 |
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Journal
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The Journal of infectious diseases |
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Title
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Naturally Occurring Single Amino Acid Substitution in the L1 Major Capsid Protein of Human Papillomavirus Type 16: Alteration of Susceptibility to Antibody-Mediated Neutralization. |
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Author
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Ning T,Wolfe A,Nie J,Huang W,Chen XS,Wang Y |
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Evidence
|
However, the remaining 21 mutants (P55L, P55-, A136T, A137S, N138K, A139E, N143K, N181S, A266T, G281W, S282P, A284V, N285H, N285T, S302L, T353P, K361E, T389S, C428W, K430Q, and K430H) showed substantially different neutralization titers from that of the reference PsVs (Figure 1).
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HPV Mutation Detail Information