|
Mutation Information
|
Mutation Site
|
A131G |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
E6 |
|
Combined Mutation
|
e6.R10G+e6.L83V |
|
Nucleotide_Mutation
|
R10G |
|
Genotype/Subtype
|
HPV16 |
|
Viral Reference
|
K02718.1
|
|
Country
|
China |
Literature Information
|
PubMed PMID
|
24099556
|
|
Disease
|
Cervical intraepithelial neoplasia;
Cervical carcinoma
|
|
Published Year
|
2013 |
|
Journal
|
BMC cancer |
|
Title
|
Genetic variations of E6 and long control region of human papillomavirus type 16 from patients with cervical lesion in Liaoning, China. |
|
Author
|
Sun Z,Lu Z,Liu J,Wang G,Zhou W,Yang L,Liu C,Wang B,Ruan Q |
|
Evidence
|
Nucleotide variations of E6 included 4 silent mutations of G94A, G176A, C215T and T241G and 5 missense mutations of A131C, T178G/A, C335T, T350G and A442C, which led to amino acid variations of R10G, D25E, H78Y, L83V and E113D, respectively.
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HPV Mutation Detail Information