HBV Mutation Detail Information

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Mutation Information

Mutation Site	A128V
Mutation Type	Amino acid level
Gene/Protein/Region Type	S
Relevant Drug	lamivudine (LAM)

Literature Information

PubMed PMID	16928212
Disease	Chronic hepatitis B
Published Year	2006
Journal	Journal of gastroenterology and hepatology
Title	Association of core promoter mutations with viral breakthrough in chronic hepatitis B patients on long-term lamivudine therapy.
Author	Kazim SN,Chauhan R,Das BC,Sarin SK
Evidence	In two of the eight patients naturally occurring S‐gene mutations were detected in baseline samples. In one patient it resulted in P120S (Fig.1a) and in another in A128V (Fig.1b) amino acid substitutions.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation