HIV Mutation Detail Information

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Mutation Information

Mutation Site	A128T
Mutation Type	Amino acid level
Gene/Protein/Region Type	IN
Relevant Drug	bictegravir (BIC);emtricitabine (FTC);tenofovir alafenamide
Country	Australia;Europe;North America

Literature Information

PubMed PMID	31430369
Disease	HIV infection/AIDS
Published Year	2019
Journal	The Journal of antimicrobial chemotherapy
Title	Switching to bictegravir/emtricitabine/tenofovir alafenamide maintained HIV-1 RNA suppression in participants with archived antiretroviral resistance including M184V/I.
Author	Andreatta K,Willkom M,Martin R,Chang S,Wei L,Liu H,Liu YP,Graham H,Quirk E,Martin H,White KL
Evidence	Other secondary INSTI-R substitutions observed were: F121C, A128T and G140S (n=2 each), and S153A (n=1).

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation